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KMID : 1377020160130060612
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Tissue Engineering and Regenerative Medicine
2016 Volume.13 No. 6 p.612 ~ p.621
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Current advances in three-dimensional tissue/organ printing
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Park Jeong-Hun
Jang Jin-Ah
Lee Jung-Seob
Cho Dong-Woo
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Abstract
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Three-dimensional (3D) tissue/organ printing is a major aspect of recent innovation in the field of tissue engineering and regenerative medicine. 3D tissue/organ printing aims to create 3D living tissue/organ analogues, and have evolved along with advances in 3D printing techniques. A diverse range of computer-aided 3D printing techniques have been applied to dispose living cells together with biomaterials and supporting biochemical factors within pre-designed 3D tissue/organ analogues. Recent developments in printable biomaterials, such as decellularized extracellular matrix bio-inks have enabled improvements in the functionality of the resulting 3D tissue/organ analogues. Here, we provide an overview of the 3D printing techniques and biomaterials that have been used, including the development of 3D tissue/organ analogues. In addition, in vitro models are described, and future perspectives in 3D tissue/organ printing are identified.
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KEYWORD
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3D tissue/organ printing, Bio-ink, 3D tissue/organ analogue, In vitro tissue model, Tissue engineering and regenerative medicine
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